Thanks for your inquiry. Aspose components are highly scalable and lightning fast. Office applications were not designed to be simultaneously used by hundreds and thousands of users; however, Aspose components are designed for just that. Our components are a true .NET solution and perform flawlessly whether on a single server powering a single application or on a load balanced web farm powering an enterprise wide application.
There is no documentation available about best practices for performance of document generation. I suggest you please read following documentation link for your kind reference. Hope this helps you.
Could you please share what exact you want to achieve by using Aspose.Words? We will then provide you more information about your query.