Thank you for contacting Aspose support team.
Aspose.Email is a rich library and it does not require Outlook or any other mail client for creation and sending or receving the mails. It provides features to work with mails, outlook, exchanges, Pop3, Imap, EWS, Gmail, Thunderbird and mails verification. You may please visit following link to create and send email (without using Outlook):
Sending and Forwarding messages
Please give a try to the sample codes and feel free to write us back if you have any other query in this regard.