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Could not load file or assembly 'Aspose.Words'

Greetings
We are a Novell Shop that has a custom app that has been built for us.
The app is running on a 2003 32 bit server.
not part of a domain or active directory
People access this app via its web application intervace and well as unc mappings.
All of a sudden we are getting this error and not sure where to look for resolution.

LOCATION OF ERROR: /Reports/Letter.aspx MESSAGE: GenerateDocument.ImpersonatedUser= CWSV-WCAPP\Cmac Could not load file or assembly 'Aspose.Words, Version=8.0.0.0, Culture=neutral, PublicKeyToken=716fcc553a201e56' or one of its dependencies. Access is denied. STACK TRACE: at Web.Letter.btnGenerateDocument_Click(Object sender, EventArgs e) in C:\inetpub\wwwroot\AL_Web\Web\Reports\Letter.aspx.vb:line 109 at System.Web.UI.WebControls.Button.OnClick(EventArgs e) at System.Web.UI.WebControls.Button.RaisePostBackEvent(String eventArgument) at System.Web.UI.WebControls.Button.System.Web.UI.IPostBackEventHandler.RaisePostBackEvent(String eventArgument) at System.Web.UI.Page.RaisePostBackEvent(IPostBackEventHandler sourceControl, String eventArgument) at System.Web.UI.Page.RaisePostBackEvent(NameValueCollection postData) at System.Web.UI.Page.ProcessRequestMain(Boolean includeStagesBeforeAsyncPoint, Boolean includeStagesAfterAsyncPoint)

The developer is indicating that the box it self is somehow loosing its permissions on this folder but im not technical enough to understand this error or what he is infering.
Any thoughts on what i might be able to do to dig a bit further.

Hi

Thanks for your inquiry. It is difficult to tell you what the exact reason of this problem is. Actually different things can cause such kind of error. I think the following article could answer some of your question and maybe help you to resolve the problem:
http://blogs.msdn.com/b/dougste/archive/2006/09/05/741329.aspx
Best regards,