Thanks for your interest in our products.
Aspose.Pdf allows you to create a template PDF document and you can also use DataSet to import values into PDF document. As per your requirement, you can create a PDF form and then use the DataSet to import values into Form fields during the process of it's generation. You may also create a Template PDF form without importing data and later on, you can use Aspose.Pdf.Kit to import data/fill PDF form fields. Aspose.Pdf.Kit is a component which is used to manipulate/edit any existing PDF documents. But I'm afraid your requirement of specifying the Formulaset is currently not supported.
Please visit the following links for information on topics related to Aspose.Pdf
For information on filling form fields using Aspose.Pdf.Kit, please visit Fill PDF Form and Form Fields
FYI, once the Excel worksheet is generated/accessed using Aspose.Cells, you can save the file into PDF format. For more information, please visit Convert an XLS File to PDF Format
Please correct me if I've not properly understood your requirement. In case of any further query, please feel free to contact.