@Acton,
Thanks for the sample file.
I think you may first import your datatable to Excel spreadsheet via Aspose.Cells APIs, see the document for your reference:
https://docs.aspose.com/display/cellsnet/Import+Data+into+Worksheet#ImportDataintoWorksheet-ImportingfromDataTable
Regarding formatting (e.g set font text bold, set text wrapped in the cells, etc.), once you have imported data from DataTable to Excel worksheet, you may create Style object(s) and specify your desired formatting attributes (you may also create StyleFlag object(s) and then set the relevant options on), then you may apply formatting to the whole row, complete range, column or cells for your needs, see the documents for your reference:
https://docs.aspose.com/display/cellsnet/Data+Formatting
https://docs.aspose.com/display/cellsnet/Dealing+with+Font+Settings
See the following code segment for your reference:
e.g
Sample code:
Worksheet _worksheet = workbook.Worksheets["Daily Brief Report"];
//Create a style object
Aspose.Cells.Style style = workbook.CreateStyle();
//Set wrapping text on
style.IsTextWrapped = true;
//set the font text bold
style.Font.IsBold = true;
StyleFlag flag = new StyleFlag();
flag.WrapText = true;
flag.FontBold = true;
//Apply the style to the header row (bold text and text is wrapped)
_worksheet.Cells.ApplyRowStyle(0, style, flag);
//Your code goes here.
//...........
//.........
_worksheet.AutoFitRows();
Hope, this helps a bit.
Thank you.