Well, I think you may export your worksheet data to fill a datatable or array using Cells.ExportDataTable or Cells.ExportArray methods.
//You can open the excel file using Aspose.Cells.Workbook.Open() method, now export / fill a datatable based on the sheet data in the cells, finally use ADO.NET API or your own code to fill/update the SQL Server Database table(s) or other db tables for your need.//
Workbook wb = new Workbook();
Worksheet ws = wb.Worksheets;
int trows = ws.Cells.MaxDataRow;
int tcols = ws.Cells.MaxDataColumn;
DataTable dt = ws.Cells.ExportDataTable(0, 0,trows, tcols, true);
Hope, this helps you.
For further reference, please see the document: